Department of Biomedical Engineering

dr. S. (Sandra) Hofmann Boss - Expertise

Hofmann Boss, dr. S.
Technische Universiteit Eindhoven
P.O. Box 513
Department of Biomedical Engineering
Orthopaedic Biomechanics
Assistant Professor (UD)
Assistant Professor
GEM-Z 4.124
+31 40-247 3494
T (internal):


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Sandra Hofmann is appointed assistant professor (UD) in the Orthopaedic Biomechanics group of Prof. Keita Ito at the Department of Biomedical Engineering, Eindhoven University of Technology. Her main research interests are tissue engineering of skeletal tissues using human mesenchymal stem cells. Particular focus lies in the investigation of mechanobiological questions, such as how mechanical loads are applied to and sensed by cells in a 3D environment and how the cells react to these in terms of matrix production. To take into account the time-dependency of a developing tissue, longitudinal imaging methods – for example with micro-computed tomography - are applied. She graduated 2002 in Pharmaceutical Sciences from the University of Basel, Switzerland. After seven months as a visiting scientist at Tufts University in Medford/Boston, USA, where she was introduced into the field of biomedical engineering and silk fibroin, she started her PhD at the Institute of Pharmaceutical Sciences of ETH Zurich under the supervision of Prof. Hans P. Merkle, Prof. David Kaplan and Prof. Lorenz Meinel.

She received her PhD degree including the silver medal of the ETH Zurich for outstanding PhD theses in 2007. She then joined the Institute for Biomechanics at ETH Zurich as a PostDoc to integrate biological expertise into an engineering environment and soon took over the lead of the Skeletal Tissue Engineering Group.


Her research interest include

-          Bone tissue engineering

-          Mechanobiology

-          Bioreactors

-          Longitudinal monitoring

-          Human mesenchymal stem cells

-          Silk fibroin scaffolds