Electron tomography shows molecular anchoring within a layer-by-layer film
ArticleVos, M.R.J., Breurken, M., Leclère, P.E.L.G., Bomans, P.H.H., Haas, de, F., Frederik, P.M., Jansen, J.A., Nolte, R.J.M. & Sommerdijk, N.A.J.M. (2008). Electron tomography shows molecular anchoring within a layer-by-layer film. Journal of the American Chemical Society, 130(38), 12608-12609. In Scopus Cited 3 times.
The layer-by-layer self-assembly of thin films consisting of alternating layers of DNA and bis-urea nanoribbons prevents diffusion of the components within the film and allows the anchoring of biotinylated molecules through molecular recognition in a predetermined layer of the film. Electron tomography demonstrates with nanometer precision the location of gold-labeled streptavidin bound to the incorporated biotinylated molecules.