Photochemical transformations accelerated in continuous-flow reactors : basic concepts and applications
ArticleSu, Y., Straathof, N.J.W., Hessel, V. & Noel, T. (2014). Photochemical transformations accelerated in continuous-flow reactors : basic concepts and applications. Chemistry - A European Journal, 20(34), 10562-10589. In Scopus Cited 116 times.
Continuous-flow photochemistry is used increasingly by researchers in academia and industry to facilitate photochemical processes and their subsequent scale-up. However, without detailed knowledge concerning the engineering aspects of photochemistry, it can be quite challenging to develop a suitable photochemical microreactor for a given reaction. In this review, we provide an up-to-date overview of both technological and chemical aspects associated with photochemical processes in microreactors. Important design considerations, such as light sources, material selection, and solvent constraints are discussed. In addition, a detailed description of photon and mass-transfer phenomena in microreactors is made and fundamental principles are deduced for making a judicious choice for a suitable photomicroreactor. The advantages of microreactor technology for photochemistry are described for UV and visible-light driven photochemical processes and are compared with their batch counterparts. In addition, different scale-up strategies and limitations of continuous-flow microreactors are discussed.