Towards synthetic enzymes
At the Supramolecular Chemistry and Catalysis group, we work towards the integration of biological and chemical processes to generate non-natural conversions in complex media. We explore the exciting opportunities that arise from the integration of polymer chemistry, supramolecular chemistry and stereochemistry with the novel field of bio-orthogonal chemistry, that studies chemical reactions to augment biochemical processes. Using this integrated approach, we focus on the design and synthesis of (supramolecular) copolymers that form nanometer-sized structures with the aim to achieve efficient and selective catalysis in water and in complex cellular media. Developing such complex molecular systems based on non-covalent, reversible interactions, and understanding the mechanisms underlying their formation, will provide a solid foundation to progress towards in vivo applications.
Read moreMeet some of our Researchers
Recent Publications
Our most recent peer reviewed publications
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Spectrally PAINTing a Single Chain Polymeric Nanoparticle at Super-Resolution
Journal of the American Chemical Society (2022) -
Developing Pd(ii) based amphiphilic polymeric nanoparticles for pro-drug activation in complex media
Molecular Systems Design and Engineering (2022) -
How Subtle Changes Can Make a Difference – Reproducibility in Complex Supramolecular Systems
Angewandte Chemie - International Edition (2022) -
Direct C-H trifluoromethylation of (hetero)arenes in water enabled by organic photoredox-active amphiphilic nanoparticles
Chemistry : A European Journal (2022) -
Controlling the Processability and Stability of Supramolecular Polymers Using the Interplay of Intra- and Intermolecular Interactions
Macromolecules (2022)

Contact
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Visiting address
Helix, STO 4.45Het KranenveldEindhovenNetherlands -
Secretarym.jiricka@ tue.nl