Towards synthetic enzymes
At the Supramolecular Chemistry and Catalysis group, we work towards the integration of biological and chemical processes to generate non-natural conversions in complex media. We explore the exciting opportunities that arise from the integration of polymer chemistry, supramolecular chemistry and stereochemistry with the novel field of bio-orthogonal chemistry, that studies chemical reactions to augment biochemical processes. Using this integrated approach, we focus on the design and synthesis of (supramolecular) copolymers that form nanometer-sized structures with the aim to achieve efficient and selective catalysis in water and in complex cellular media. Developing such complex molecular systems based on non-covalent, reversible interactions, and understanding the mechanisms underlying their formation, will provide a solid foundation to progress towards in vivo applications.
Read moreMeet some of our Researchers
Project Related Publications
Our most recent peer reviewed publications
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Amphiphilic polymeric nanoparticles enable homogenous rhodium-catalysed NH insertion reactions in living cells
Nanoscale (2023) -
Amphiphilic polymeric nanoparticles enable homogenous rhodium-catalysed NH insertion reactions in living cells
Nanoscale (2023) -
Protein-Inspired Control over Synthetic Polymer Folding for Structured Functional Nanoparticles in Water
ChemPlusChem (2023) -
Protein-Inspired Control over Synthetic Polymer Folding for Structured Functional Nanoparticles in Water
ChemPlusChem (2023) -
Dynamic covalent networks with tunable dynamicity by mixing acylsemicarbazides and thioacylsemicarbazides
Journal of Polymer Science (2023)

Contact
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Visiting address
Helix, STO 4.45Het KranenveldEindhovenNetherlands -
Visiting address
Helix, STO 4.45Het KranenveldEindhovenNetherlands -
Secretarym.jiricka@ tue.nl