Molecular Biosensing
The MBx group develops technologies based on micro- and nanoparticles for monitoring patients and for treating diseases. Towards this goal, the unique approach of MBx is to use advanced optical imaging techniques that quantify molecular processes with single molecule resolution within complex biomacromolecular environments.
Quantify molecular processes with single molecule resolution
The MBx group creates concepts in the field of molecular biosensing with diagnostic and therapeutic healthcare perspectives. Combining nanotechnology, molecular engineering and single molecule imaging technologies we aim to measure with ultimate sensitivity biomolecules implicated in a variety of diseases, such as cancer, immunology, and cardiology.
Read moreResearch Areas
UPCOMING TECHNOLOGIES FOR CLINICAL IMMUNOLOGY
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CBL Teaching Toolkit Demo Coffee Session (23-04-24)
Learn more about the Challenge Based Learning Teaching Toolkit, and discover how to transform your courses into engaging, hands-on learning…
Student Take-Over: Goethe
April 23, 2024 / Corona hall, Luna building
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innoVisits (23-04-24)
Get a 360° view of TU/e innovation Space during this two hour program, hosted by students from our community.
EAISI lecture by visiting Professor Alan Said
Personalization through the Evolution of Tastes
The Global Race for Nuclear Fusion is On
April 24, 2024 12:40 PM / Blauwe Zaal, Auditorium
EWUU Alliance Annual Conference 2024
April 24, 2024 12:00 PM / Utrecht
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EWUU Annual Conference 2024: 'Navigating Transitions'
April 24, 2024 12:00 PM / TivoliVredenburg, Utrecht
The Gate Academy | Workshop
April 24, 2024 3:30 PM / Room 2.18 - Alpha Hub, 2nd floor - Eeuwsel 57
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HumAIn Dialogues lecture: Mahault Albarracin
Active in cognitive science, psychology, and technology, specifically in active inference, gender fluidity, affordances, and scripts.
The Gate Academy | Training
April 25, 2024 1:30 PM / Room 2.12 - Alpha Hub, 2nd floor - Eeuwsel 57
EIRES Lunch Lecture
12h00-13h00 | Topic: The Iron Power Cycle, status and next steps
PhD defense Alex Johannes Albertus Donkers
April 29, 2024 / TU/e Campus
Work with us!
Building a better future for our global society? Join our research team and be part of the thriving community at Eindhoven University of Technology.
Working at the department of Biomedical Engineering or Applied Physics
We are continuously looking for enthusiastic and motivated students and postdocs. If you would like to work in a great environment at TU/e, please contact one of the staff members for more information.
Meet some of our Researchers
Recent Publications
Our most recent peer reviewed publications
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Arthur L. Hendriks,Mathias Dolci,Mildred S. Cano-Velázquez,Luca Picelli,Peter Zijlstra,Ewold Verhagen,Andrea Fiore
Detecting single nanoparticles using fiber-tip nanophotonics
Optica (2024) -
Alissa D. Buskermolen,Claire M.S. Michielsen,Arthur M. de Jong,Menno W.J. Prins
Towards continuous monitoring of TNF-α at picomolar concentrations using biosensing by particle motion
Biosensors and Bioelectronics (2024) -
Swayandipta Dey,Francesco Sciortino,Emanuela Zaccarelli,Peter Zijlstra
Biomolecular interactions on densely coated nanoparticles
Nanoscale (2024) -
Hailin Fu,Jingyi Huang,Joost J.B. van der Tol,Lu Su,Yuyang Wang,Swayandipta Dey,Peter Zijlstra,George Fytas,Ghislaine Vantomme,Patricia Y.W. Dankers
Supramolecular polymers form tactoids through liquid–liquid phase separation
Nature (2024) -
Tania Patiño,Joaquin Llacer-Wintle,Sílvia Pujals,Lorenzo Albertazzi,Samuel Sánchez
Unveiling protein corona formation around self-propelled enzyme nanomotors by nanoscopy
Nanoscale (2024)
News
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Education
Check out all our courses
The research group Molecular Biosensing for Medical Diagnostics provides courses and projects in the bachelor's and master's programs of the departments of Biomedical Engineering and Applied Physics. Furthermore, we offer a broad range of projects for students to work on in the research group.
PhD Theses
Video on Plasmonic Biosensing using Metal Nanoparticles
Metal nanoparticles provide the possibility to detect single molecules without the need for labeling, enabling the direct detection of non-absorbing species [1]. A molecule that binds to receptors on the surface of a particle induces a change in the local refractive index that in turn results in a change of color due to a shift of the plasmon resonance [2,3]. This animation illustrates the real-time detection of plasmon shifts induced by molecules binding to functionalized single gold nanorods. The plasmon shifts are measured by monitoring scattering intensities of many particles simultaneously and in real-time [4].
Contact
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Visiting address
FluxGroene Loper 195612 AE EindhovenNetherlands -
Visiting address
FluxGroene Loper 195612 AE EindhovenNetherlands -
Postal address
Department of Biomedical Engineering & Department of Applied PhysicsP.O.Box 5135600 MB EindhovenNetherlands -
Postal address
Department of Biomedical Engineering & Department of Applied PhysicsP.O.Box 5135600 MB EindhovenNetherlands -
Secretary
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Secretary