Orthopaedic Biomechanics
We explore and develop (regenerative) treatment strategies for orthopaedic injuries and disorders based on a thorough understanding of musculoskeletal tissue mechanobiology and biomechanical function.
Novel treatment strategies for an ever-active ageing population
Human cells produce, maintain and adapt musculoskeletal tissues such as bone and cartilage as a response to their biophysical environment, both in health and disease. In our ever-aging population, orthopaedic injuries and degenerative diseases have become more prevalent, with an increasing socioeconomic impact. Current treatment methods with purely synthetic devices may be limited in view of the increasing longevity and high level of activity of modern day humans. The Orthopaedic Biomechanics research group combines engineering and biology to expand our understanding of musculoskeletal tissues and to develop (regenerative) treatment strategies. These are currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments.
Research Lines
Related Events
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Dutch Technology Festival
June 8, 2023 9:00 AM / Klokgebouw, Strijp S Eindhoven
PhD defense Caterina Rizzo
June 9, 2023 / TU/e Campus
PhD defense Robert Paul van Dongen
June 9, 2023 / TU/e Campus
EIRES Lunch lecture
12h00-13h00 with Ioulia Ossokina & Theo Arentze
TU/e Green Week 2023
June 12, 2023 / Various buildings around campus
PhD defense Jiajia Zhang
June 13, 2023 / TU/e Campus
Meet the student teams
Want to do more than just studying? Join a student team and put theory into practice, develop your (soft) skills and work on innovations!
PhD defense Bente Aminhan Somsen
June 13, 2023 / TU/e Campus
PhD defense Mohammad Hasani
June 13, 2023 / TU/e Campus
Transformative Research for Sustainability
June 13, 2023 10:45 AM / Filmzaal de Zwarte Doos
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Final presentations ISBEP
June 14, 2023 2:00 PM / TU/e innovation Space / Matrix 1.345
PhD defense Nicolas Daub
June 14, 2023 / TU/e Campus
ERC Proof of Concept grant for screening drug effects on bone ex vivo
Dr. Sandra Hofmann has been awarded an ERC Proof of Concept grant for her project ‘An ex vivo platform to screen drug effects on bone’. In collaboration with TU/e Innovation Space, LifeTec Group, and OsteoPharma, this BoneScreen platform will be validated for its efficacy in screening the effect of drugs on bone cells longitudinally.
NWO Demonstrator grant for ‘ultrACLean’
Dr. Jasper Foolen, together with Prof. Jan de Boer, was awarded an NWO Demonstrator grant for the project: “ultrACLean: A novel decellularized off-the-shelf human graft for improved anterior cruciate ligament reconstruction”.
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- Other news of the department of Biomedical Engineering
International research project iPSpine
Chronic lower back pain (LBP) is the leading cause of disability and morbidity worldwide. More than 700 million people globally of all ages are affected each year. LBP is a major cause of reduced activity and work absence, and imposes an economic burden of nearly ~€240 billion every year in the EU. iPSpine aims to investigate and develop a new therapy for LBP using induced pluripotent stem cells (iPSCs). The project will develop an advanced therapy using iPS-technology and smart biomaterials that will be translated from laboratory models into a clinically relevant animal model. By the end of the project, the therapy should be ready for advancement to the first human clinical trial.
Meet some of our Researchers
Recent Publications
Our most recent peer reviewed publications
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Stefan J.A. Remmers,Keita Ito,Sandra Hofmann
The effects of seeding density and osteoclastic supplement concentration on osteoclastic differentiation and resorption
Bone Reports (2023) -
Stefan J.A. Remmers,Bregje W.M. de Wildt,Keita Ito,Sandra Hofmann
Tuning the resorption-formation balance in an in vitro 3D osteoblast-osteoclast co-culture model of bone
Bone Reports (2023) -
Daan Martijn Janssen,Marieke van der Steen,Eugenie Delvaux,Hans Hendriks,Rob P.A. Janssen
Digital health applications to establish a remote diagnosis for orthopedic knee disorders
Journal of Medical Internet Research (2023) -
Sander C. van Eijck,Daan M. Janssen,Maria C. van der Steen,Eugenie J.L.G. Delvaux,Johannes G.E. Hendriks,Rob P.A. Janssen
Digital Health Applications to Establish a Remote Diagnosis of Orthopedic Knee Disorders
Journal of Medical Internet Research (2023) -
Celien A.M. Jacobs,Esther E.A. Cramer,Aylvin A. Dias,Harold Smelt,Sandra Hofmann,Keita Ito
Surface modifications to promote the osteoconductivity of ultra-high-molecular-weight-polyethylene fabrics for a novel biomimetic artificial disc prosthesis
Journal of Biomedical Materials Research, Part B: Applied Biomaterials (2023)
Student opportunities
The Orthopaedic Biomechanics group provides courses and projects in the bachelor's and master's program.
Partners and Cooperation
The Orthopaedic Biomechanics groups collaborates with different partners in academia and industry. Collaborations are within the Netherlands, but also go beyond borders.
Contact
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Visiting address
Building 15, Gemini-South (room 4.115)Groene Loper5612 AZ EindhovenNetherlands -
Postal address
Department of Biomedical EngineeringP.O. Box 5135600 MB EindhovenNetherlands -
Secretary
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Teamlead