Department of Biomedical Engineering

Orthopaedic Biomechanics

We explore and develop (regenerative) treatment strategies for orthopaedic injuries and disorders based on a thorough understanding of musculoskeletal tissue mechanobiology and biomechanical function.

Novel treatment strategies for an ever-active ageing population

Human cells produce, maintain and adapt musculoskeletal tissues such as bone and cartilage as a response to their biophysical environment, both in health and disease. In our ever-aging population, orthopaedic injuries and degenerative diseases have become more prevalent, with an increasing socioeconomic impact. Current treatment methods with purely synthetic devices may be limited in view of the increasing longevity and high level of activity of modern day humans. The Orthopaedic Biomechanics research group combines engineering and biology to expand our understanding of musculoskeletal tissues and to develop (regenerative) treatment strategies. These are currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments.

Research Lines

Vidi grant for bone model

Dr. Sandra Hofmann was awarded a Vidi grant for her project ‘A miniature bone model’.
The interaction between various cells within bone is still poorly understood. The goal of this project is to develop miniature bones from human cells in the laboratory. These tissues will be used to study bone turnover in healthy versus diseased bone and will consecutively be used to develop specific drug therapies.

Meet some of our Researchers

Recent Publications

Our most recent peer reviewed publications

Student opportunities

The Orthopaedic Biomechanics group provides courses and projects in the bachelor's and master's program.

Partners and Cooperation

The Orthopaedic Biomechanics groups collaborates with different partners in academia and industry. Collaborations are within the Netherlands, but also go beyond borders.