Bone Function and Structure

The main function of bone is to provide strength and stiffness to the musculoskeletal system. This function is most often compromised by trauma either primarily or secondary to diseases such as osteoporosis, a common condition of altered bone mass and micro-architecture. This relationship between bone morphology, material properties, and strength is explored with refined imaging methods and computational models.

Our goal is to estimate bone strength for assessment of fracture risk as well as to predict how this may be altered by possible treatments. We also develop effective preventive measures against osteoporosis, by exploiting the natural effects of mechanical forces on bone mass. This is explored through computational and in vivo experiments.