Precision Medicine
The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.
Nanotechnology for immunotherapy
Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.
Meet some of our Researchers
Recent Publications
Our most recent peer reviewed publications
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Joslyn Quick,Nancy Dos Santos,Miffy H.Y. Cheng,Nisha Chander,Cedric A. Brimacombe,Jayesh Kulkarni,Roy van der Meel,Yuen Yi C. Tam,Dominik Witzigmann,Pieter R. Cullis
Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy
Journal of Controlled Release (2022) -
Mandy M.T. van Leent,Bram Priem,David P. Schrijver,Anne de Dreu,Stijn R.J. Hofstraat,Robby Zwolsman,Thijs J. Beldman,Mihai G. Netea,Willem J.M. Mulder
Regulating trained immunity with nanomedicine
Nature Reviews. Materials (2022) -
Ewelina Kluza,Thijs J. Beldman,Annelie Shami,Edwin R. Scholl,Tsveta S. Malinova,Anita E. Grootemaat,Nicole N. van der Wel,Isabel Gonçalves,Stephan Huveneers,Willem J.M. Mulder
Diverse ultrastructural landscape of atherosclerotic endothelium
Atherosclerosis (2021) -
Abraham J.P. Teunissen,Marianne E. Burnett,Geoffrey Prévot,Emma D. Klein,Daniel Bivona,Willem J.M. Mulder
Embracing nanomaterials' interactions with the innate immune system
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology (2021) -
Roy van der Meel,Sam Chen,Josh Zaifman,Jayesh A. Kulkarni,Xu Ran Sabrina Zhang,Ying K. Tam,Marcel B. Bally,Raymond M. Schiffelers,Marco A. Ciufolini,Pieter R. Cullis
Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery
Small (2021)
Contact
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Postal address
Helix BuildingPostbus 5135600 MB EindhovenNetherlands -
Postal address
Helix BuildingPostbus 5135600 MB EindhovenNetherlands -
Visiting address
Helix Building (STO 3.39)De Groene Loper 35612 AE EindhovenNetherlands -
Visiting address
Helix Building (STO 3.39)De Groene Loper 35612 AE EindhovenNetherlands -
Secretary