Projects

Bachelor End Projects (BEPs)

BEP projecten starten in onze groep in kwart 4. De projecten sluiten aan bij lopende onderzoeken, waarover je hier meer informatie kunt vinden.

Voor meer informatie kun je mailen naar bep.stbe@tue.nl

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Evaluation of RNA silencing plasmids for Notch signalling modulation

One of the methods to study the role of a protein is silencing through RNA interference. With silencing one blocks the production of a...

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

MRI based 3D finite element modelling of deep tissue injury

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

What are the histological effects of loading muscles tissue?

The goal of this study is to determine the physiological response of the muscle to loading using histology. Tibialis anterior muscles which...

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Measuring shear stress

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Modelling skin viscoelasticity

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Biodegradable electrospun cardiovascular prosthesis: accelerated degradation and mechanical characterization in vitro

This project intends to characterize PCL-based materials for cardiovascular implants, and measure some of their most relevant mechanical...

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Successful protection against cancer

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Numerical algorithms to predict cellular traction forces

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Mechanical testing of soft biological tissues

In this project, we would like to compare two methods of mechanical testing: our proposed (non-destructive) bulge test method, to a standard...

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Vascular graft endothelization: a way towards improved hemocompatibility?

The aim of this project is to characterize the growth dynamics and phenotype of ECs seeded on novel electrospun materials with different...

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

The influence of heart valve geometry on long-term functionality

A finite element framework is readily available in which the student can generate finite element meshes with different valve geometries by...

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Unraveling cross-talk between macrophages and (myo)fibroblasts for in situ tissue engineering

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Controlling cell adhesion to functionalized surfaces

Bachelor End Project of Soft Tissue Engineering and Mechanobiology

Incorporation of antibacterial agents in artificial vascular access grafts for haemodialysis

Master thesis projects

The STEM group provides a monthly information and consultation meeting for (future) master students.

The meetings are hosted by two of our staff members and take place during a Monday lunch hour, somewhere in the Gemini building (mostly in the CIC).

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Tissue engineering of the corneal stroma by simultaneously guiding the overall tissue shape and architecture of collagen.

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Stiffness measurement for cardiac microtissues, the effect of stiffness on tissue contractility

In this project, you will explore the possibilities of measuring microtissue stiffness and develop a protocol for these measurements. When...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Biomechanical properties of the prolapsed vagina wall in women

The aim of the study is to assess structure-function  properties of vaginal wall tissue of women with a POP, where mechanical properties...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Tissue engineering solutions for the lower urinary tract

This project emphasizes on the feasibility of new tissue engineering techniques and technologies to support the regeneration and function of...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Pull it like a cell

In this Master’s research project, you will explore the possibilities of circumventing these challenges by developing a novel technique to...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Immunoengineering: Elucidating the influence of biophysical and biomechanical cues on human macrophages

In situ TE (TE) is a new approach for obtaining living replacement grafts for damaged heart valves and blood vessels, superior to existing...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Modeling cell mechanosensing

In this Master’s research project, you will use a finite element modeling based on the tensegrity approach to describe the biomechanical...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Influence of prolonged heart valve storage on donor valve functionality and durability

In this Master’s research project, you will study several human aortic heart valves that have been stored in either liquid nitrogen (-196°C)...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

The role of hemodynamic loading on the link between vimentin and Notch signaling

In short, the aim of the project is to create vimentin knock out vascular cells to study the relation between vimentin, Notch signalling and...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

The effect of cell mechanics on valvular cell fate

In this project you will study the interplay between mechanical (hemodynamic) cues the cells are exposed to and the cell-cell interactions...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Why is cell therapy for cardiac regeneration still a myth? A 3D cardiac hydrogel model system to unravel the myth

In this Master Thesis Project, the goal is to develop a method to create a 3D hydrogel culture system with both anisotropic and isotropic...

Master Thesis Project of Soft Tissue Engineering and Mechanobiology

Keratocyte alignment and ECM production under influence of in vivo-like cues

One of the characteristics of the stromal layer is the fact that keratocytes develop and maintain the surrounding collagen lamellae in an...