Arjan Hazegh Nikroo (Helmond, 1996) received his Bachelor and Master degree in Biomedical Engineering at Eindhoven University of Technology in 2018 and 2022, respectively. For his master thesis in the Chemical Biology group of prof. Luc Brunsveld, he engineered phosphoregulated scaffold proteins by fusing 14-3-3 proteins to inhibitory peptide modules that reversibly block and liberate the 14-3-3 binding pockets upon phosphorylation and dephosphorylation. During a subsequent internship at Ambagon Therapeutics in Eindhoven, he developed a fluorescence polarization multiplex selectivity assay for compounds that stabilize 14-3-3 protein-protein interactions. To complete his degree, Arjan performed an additional internship at the Discovery & Technology department of MSD Boxmeer. Here, he focused on the recombinant expression, purification and characterization of monomeric and dimeric antigen-specific IgA monoclonal antibodies. As of May 2022, Arjan is a PhD candidate in the Bio-Organic Chemistry group of prof. Jan van Hest. His research is centered on the bottom-up engineering of protein-mediated communication mechanisms between coacervate-based artificial cells and living cells.
No ancillary activities