Hossein focuses on the translation of Magnetic Artificial Cilia technology to industrial applications. Artificial cilia are synthetic hair-like nano to micro-meter size structures that can be actuated using a magnetic field. Hossein makes bridges between TU/e and industry by: Consulting with academic and industrial experts to smoothen transfer of the artificial cilia technology towards commercial purposes; Writing grant proposals to enhance the technology readiness level; Establishing collaborations to mature the technology; Providing end-user perspective for researchers at TU/e. His main activities at TU/e are in the following fields: Organ on a chip, Diagnostic devices, Microfluidics, Biosensors.
Hossein obtained his BSc in Mechanical engineering from University of Tehran, Iran in 2011, and then moved to the Netherlands to join Jaap den Toonder’s group at Eindhoven University of Technology for his MSc. In collaboration with Philips Research, he worked on smart materials and switchable micromixers in microfluidic devices for his master's thesis. Inspired by the potentials of microfluidics, he started his PhD in the same group in 2013 on integrating electro-spun scaffolds in organ on chips to study cancer cell invasion. During his PhD, he collaborated with two medical centres using the technology he developed to study the role of E-cadherin in breast cancer invasion and to model bone-cartilage interface in osteoarthritis. After receiving his PhD in 2018, he moved to the industry to develop organ on chip technologies for life scientists, a collaboration between TNO (Microbiology and metabolic Health Research departments) and Utrecht University (Group of Roos Masereeuw, Experimental pharmacology) to develop microfluidic models of the intestine. From 2020 to 2021, he was a scientist in the same departments at TNO working on different in vitro technologies for the intestine and liver. During his time at TNO, he helped the group develop and commercialize Intestinal Explant Barrier Chip (IEBC), a medium throughput organ on a chip system offered as a fee for service product to the pharmaceutical and food industry. He founded an organ on a chip consultancy company on April 2021 and has joined Jaap den Toonder’s group at TU/e part time since May 2021 as a Technology Transfer Officer to work on commercialisation of the magnetic artificial cilia technology.
Capturing Essential Physiological Aspects of Interacting Cartilage and Bone Tissue with Osteoarthritis Pathophysiology: A Human Osteochondral Unit-on-a-Chip ModelAdvanced Materials Technologies (2022)
Microscopic artificial cilia - a reviewLab on a Chip (2022)
Intestinal explant barrier chipLab on a Chip (2022)
The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testingCurrent Opinion in Toxicology (2021)
Microphysiological Systems to Recapitulate the Gut–Kidney AxisTrends in Biotechnology (2021)
No ancillary activities