Maaike Bril
Department
Group

RESEARCH PROFILE
Maaike Bril is a PhD candidate in the Soft Tissue Engineering & Mechanobiology group under the supervision of prof. Carlijn Bouten and dr. Nicholas Kurniawan. Her current research focusses on a better understanding of dynamic cell-matrix interactions. In vivo, cells are subjected to a plethora of mechanical, physical and biochemical changes in their microenvironment. By using light-responsive materials, on demand changing spatiotemporal cues can be introduced towards the cells, which allows to study the influence of dynamic microenvironments on cell behavior.
Shining a light on the dynamic interplay between cells and their extracellular microenvironment.
ACADEMIC BACKGROUND
Maaike obtained her bachelor’s degree Life Science & Technology at Leiden University and TU Delft (joint degree) and completed the research master Life Science & Technology cum laude at Leiden University. She performed her master research project under the supervision of dr. Roxanne Kieltyka, working on the development of a dynamic covalent hydrogel for the differentiation and maturation of stem cell-derived cardiomyocytes. This work received an honorable mention from the KNCV for the best (bio)chemical master thesis in 2020. After graduation she started her PhD in the Soft Tissue Engineering & Mechanobiology group at TU/e, further exploring the dynamic interplay between cells and their microenvironment.
Recent Publications
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Generation of Multicue Cellular Microenvironments by UV-photopatterning of Three-dimensional Cell Culture Substrates
Journal of Visualized Experiments (JoVE) (2022) -
A Photoresponsive Hydrogel to Subject Cells On-Demand to Dynamically Changing Topographies
ICMS Symposium Living Materials (2022) -
A Photoresponsive Hydrogel to Subject Cells On-Demand to Dynamically Changing Topographies
MDR Annual Meeting 2022 (2022) -
A Photoresponsive Hydrogel to Subject Cells On-Demand to Dynamically Changing Topographies
30th Annual Meeting of the Netherlands Society for Biomaterials and Tissue Engineering (2022) -
A Photoresponsive Hydrogel to Subject Cells On-Demand to Dynamically Changing Topographies
ICMS Annual Symposium 2022 (2022)
Ancillary Activities
No ancillary activities