Roy van der Meel is Assistant Professor of Precision Medicine at the TU/e's Biomedical Engineering department. His research is focused on developing RNA-based nanotherapeutics to regulate the immune response in a highly precise manner.
Roy van der Meel studied Biomedical Sciences and Drug Innovation at Utrecht University in The Netherlands where he obtained his M.Sc. degree in 2009. He then conducted his Ph.D. research at the Utrecht University Pharmaceutics Department under supervision of Wim Hennink, Gert Storm, Robbert Jan Kok and Raymond Schiffelers. Roy's research focused on developing nanomedicines to inhibit tumor growth and angiogenesis and he obtained his Ph.D. degree in 2013. After obtaining Marie Skłodowska-Curie Action funding from the European Commission and a Veni grant from the Dutch Research Council (NWO), Roy conducted postdoctoral research in the labs of Raymond Schiffelers (University Medical Center Utrecht) and Pieter Cullis (University of British Columbia, Vancouver, BC, Canada). In 2019, Roy was appointed Assistant Professor of Precision Medicine at the TU/e's Biomedical Engineering department. His research is supported by an NWO Vidi grant awarded in 2022.
Trained immunityCell Host and Microbe (2023)
Transport by circulating myeloid cells drives liposomal accumulation in inflamed synoviumNature Nanotechnology (2023)
A nature-inspired nanodelivery platform for gene silencing in hematopoietic stem and progenitor cells(2023)
Nanomedicine approaches for in vivo cancer immunotherapyNanomedicine (2023)
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cellsNature Biomedical Engineering (2023)
Current Educational Activities
- Scientific advisor, TAONas-LUAD project
- Consultancy, Venable LLC