Full Professor

Sebastiaan Overeem

Technological developments in the area of sleep diagnostics are essential to improve the care for patients with sleep disorders, diseases with a tremendous impact on quality of life.

Group / Unit
Signal Processing Systems
Floor / room

Research Profile

Sebastiaan Overeem is Full Professor in the Signal Processing Systems group (Department of Electrical Engineering) and in the Future Everyday group (Department of Industrial Design). He is chair of Intelligent Systems for Sleep Disorders, a clinical somnologist and a neuroscientist. At TU/e, he focuses on new diagnostic methods for sleep and sleep disorders. Overeem was part of the first hypocretin studies in patients with narcolepsy. Over the last 15 years, Overeem focused on narcolepsy, including the neurophysiology of cataplexy and the biology of the hypocretin system. The hypocretin-system formed the initial connecting link to sleep in Parkinson’s disease, when it was shown that hypocretin defects are present in Parkinson’s as a cause of sleep disturbances. This work led to a research line on sleep disorders in neurodegenerative disease, which is how Overeem was first appointed researcher at Eindhoven University of Technology (TU/e). His clinical work as a sleep medicine specialist takes place at the Center for Sleep Medicine Kempenhaeghe.

Academic Background

Sebastiaan Overeem holds a PhD (2003) and MD (2004) from Leiden University. For his thesis, he did some work at the Center for Narcolepsy Research at Stanford University. After graduating, he worked as Assistant Professor in the Department of Neurology at Radboud University Medical Center from 2005 to 2015. In 2008, he also took up the position of somnologist at expertise center Kempenhaeghe. Overeem joined Eindhoven University of Technology (TU/e) as Senior Researcher in 2015 and was appointed Part-time Professor in 2017.

Ancillary Activities

No ancillary activities