All departments at TU/e conduct research that contributes to the transition to a more sustainable society in various research programs. In addition, there is multidisciplinary research taking place which comes under the strategic areas Energy, Smart Mobility and Health.

Research at TU/e does not only take place in closed laboratories, but also on the campus itself. Indeed, TU/e uses its campus as a living lab for conducting research into green solutions. In 2013 two living lab themes were designated: a Living Lab Light and a Living Lab Smart Mobility.