Bone function & structure

Dr. Bert van Rietbergen

The main function of bone is to provide strength and stiffness to the musculoskeletal system. This function is most often compromised by trauma either primarily or secondary to diseases such as osteoporosis, a common condition of altered bone mass and micro-architecture. This relationship between bone morphology, material properties, and strength is explored with refined imaging methods and computational models.

Our goal is to estimate bone strength for assessment of fracture risk as well as to predict how this may be altered by possible treatments. We also develop effective preventive measures against osteoporosis, by exploiting the natural effects of mechanical forces on bone mass. This is explored through computational and in vivo experiments.

Current projects

Recent projects

Collaborative projects

Past projects

Mechanoregulation of bone adaptation in osteoarthritits

Cox, L.G.E. (2011). Mechanoregulated bone adaptation in osteoarthritis. Eindhoven: Technische Universiteit Eindhoven. ((Co-)promot.: prof.dr. K. Ito, dr. C.C. van Donkelaar & dr.ir. B. van Rietbergen).

Simulations of bone remodeling at the cellular scale

Oers, R.F.M. van (2010). Simulations of bone remodeling at the cellular scale. Eindhoven: Technische Universiteit Eindhoven. ((Co-)promot.: prof.dr. P.A.J. Hilbers, prof.dr.ir. R. Huiskes & dr.ir. B. van Rietbergen).

In vivo assessment of changes in bone due to osteoporosis and its possible treatments

Brouwers, J.E.M. (2008). In vivo assessment of changes in bone due to osteoporosis and its possible treatments. Eindhoven: Technische Universiteit Eindhoven. ((Co-)promot.: prof.dr. K. Ito, prof.dr.ir. R. Huiskes & dr.ir. B. van Rietbergen).

Analyses of trabecular bone failure

Verhulp, E. (2006). Analyses of trabecular bone failure. Eindhoven: Technische Universiteit Eindhoven. ((Co-)promot.: prof.dr.ir. R. Huiskes & dr.ir. B. van Rietbergen).

An explanation of the onset of mechanically induced cartilage damage

Wilson W. (2005). An explanation for the onset of mechanically induced cartilage damage. Eindhoven: Technische Universiteit Eindhoven. ((Co-)promot.: prof.dr.ir. R. Huiskes, dr. C.C. van Donkelaar & dr.ir. B. van Rietbergen).