Research profile

Researchers at the department of Biomedical Engineering combine basic science (how) with engineering (how to)‏. They investigate, develop and apply engineering principles and tools to unravel the pathophysiology of diseases and enhance diagnostics, intervention and treatment.

The research comprises eleven groups ordered in three clusters:

  • Biomechanics & Tissue Engineering
  • Chemical Biology
  • Biomedical Imaging & Modelling

Thematic programs

Besides the specialism of each group, interdisciplinary research between the groups has been realized in the three thematic programs:

  1. Regenerative Medicine
    Work in the Regenerative Medicine theme applies tissue engineering, stem cell therapy, medical devices and other techniques to repair damaged or diseased tissues and organs.

  2. Molecular Imaging
    In the Molecular Imaging theme, the disciplines molecular biology and in vivo imaging are united with the aim of designing, fabricating and using specific biomarkers for:
    • visualization of cellular function and molecular process in living organisms without perturbing them
    • early detection and treatment of diseases as well as basic pharmaceutical development.
    Biomarkers have an important role in the diagnosis of cancer, neurological and cardiovascular diseases. In addition, work is being done on novel targeting and imaging strategies to improve the resolution and sensitivity of these images.

  3. Systems Biology
    The Systems Biology theme aims to enhance the shift from ‘describing’ life’s processes to ‘understanding’ them and ‘capturing’ them in validated predictive models, and even ‘managing’ or ‘controlling’ them. The scope of this theme  covers all levels from molecules to organs and humans, such as described by the transcriptome, proteome, metabolome and the physiome.