In our group we cover the following areas of computational systems biology.

Modeling and simulation of biomolecular networks and physiological systems

• Nonlinear Differential Equation models
• Parameter Sensitivity Analysis
• Feedback control in biomolecular networks

Data integration / model parameterization

• Parameter Estimation (Maximum Likelihood Estimation, Bayesian Parameter Estimation)
• Uncertainty Analysis (Prediction Uncertainty Analysis, PUA)
• Experimental Design

Multi-scale modeling in biology and biomedicine

• Modelling of adaptations in biological systems: disease progression and integration of longitudinal treatment-in-time data from patients (ADAPT, multiple time-scales)
• Spatio-temporal dynamics of metabolic networks (PDE models)