Funding for system biologists from Eindhoven and Maastricht to analyse the effect of weight loss at the molecular level

Funded by the Enabling Technologies Hotels program of ZonMw the group of Natal van Riel will analyse data from a European study on the effect of weight loss. Weight loss has a large impact on the development of chronic diseases in the overweight and obese. The large European DiOGenes trial has shown that not everybody loses weight in response to a strict weight loss diet and, furthermore, that not everybody is able to maintain that weight loss. At present, we cannot predict who will respond beneficially to these diets. Such knowledge is urgently needed in order to personalize advice to individuals who are overweight or obese. The computational method called ADAPT developed in the Computational Biology group is used to predict and better understand individual responses to weight loss and maintenance diets. The project is a collaboration with the recently established Maastricht Centre for Systems Biology (MaCSBio)