dr.ir. J. (Jasper) Foolen - Expertise

Foolen, dr.ir. J.
Address :
Technische Universiteit Eindhoven
P.O. Box 513
5600 MB EINDHOVEN
Department :
Department of Biomedical Engineering
Section :
Orthopaedic Biomechanics
Positioncategory :
Assistant Professor (UD)
Position :
Assistant Professor
Room :
GEM-Z 4.102
Tel :
+31 40-247 5318
Tel (internal) :
5318
Email :
JFoolen@tue.nl

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Expertise

  • Tendons and ligaments
  • Fibrous tissue remodeling
  • Orthopedics
  • Mechanobiology
  • Regenerative Medicine
  • Biomechanics
  • Cell-matrix interactions

Biography

Biography

Jasper Foolen joined the Orthopedic Biomechanics group at the Department of Biomedical Engineering in 2016 as an assistant professor. His main research interest is mechanobiology and regenerative strategies of tendons and ligaments.

Education

2000 BSc in Mechanical Engineering, Fontys University for Higher Education, Eindhoven, The Netherlands
2003 BSc in Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands2005 MSc in Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
2009 PhD in Orthopedic Biomechanics, Eindhoven University of Technology, Eindhoven, The Netherlands

Experience

2009 – 2013 Postdoctoral Fellow, Soft Tissue Biomechanics and Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
2013 – 2015 Marie Curie Fellow, Lab of Applied Mechanobiology, ETH Zurich, Switzerland
2015 – 2016 Group Leader, Lab for Orthopaedic Biomechanics, University Hospital Balgrist / Swiss Federal Institute of Technology (ETH Zurich)
2016 – Assistant Professor, Tendon and Ligament Mechanobiology, Orthopedic Biomechanics, Eindhoven University of Technology, Eindhoven, The Netherlands

Research profile

Jasper Foolen is Assistant Professor at the Orthopaedic Biomechanics group of the department of Biomedical Engineering. His main research interest is mechanobiology and regenerative strategies of tendons and ligaments. Tendon and ligament injuries are involved in over 30% of all musculoskeletal consultations. Over the past decades there has been limited progress in the treatment of tendinopathy and connective tissue fibrosis (scarring). It suffers from poor innate regenerative capacity, the clinical outcome of surgical interventions has remained rather poor and there is controversy concerning adequate treatment.

In his research, Jasper Foolen explores the mechanobiological processes that initiate degeneration and promote healing of tendons and ligaments. Experimental platforms (e.g. biomimetic tendons and ligaments) are exploited in combination with numerical models, to develop strategies to improve the structure and functionality of affected tendons and ligaments.

Current projects are concerned with the role of cellular junctions in tendon tissue organization, and the impact of cellular organization in 3D tissue on the healing capacity of tendon-derived cells. 

Academic background

Jasper Foolen studied Mechanical Engineering at Fontys University for Higher Education (Eindhoven, The Netherlands) and obtained his BSc in 2000. He then started his study in Biomedical Engineering at Eindhoven University of Technology (TU/e) where he obtained his BSc in 2003 and his MSc in 2005. From 2005 – 2009, he was a PhD student at the TU/e research group Orthopedic Biomechanics. In 2009 Foolen obtained his PhD with his thesis 'How periosteum is involved in long bone growth' under supervision of professors Keita Ito, Rik Huiskes and René van Donkelaar. From 2009 – 2013, he was a Postdoctoral Fellow at the TU/e research group for Soft Tissue Biomechanics and Engineering. In 2013 Foolen moved to Switzerland to become a Marie Curie Fellow at the Lab of Applied Mechanobiology at ETH Zurich. From 2015 – 2016, he was Group Leader at the Lab for Orthopaedic Biomechanics of University Hospital Balgrist / ETH Zurich. In 2016 Jasper Foolen was appointed Assistant Professor in Tendon and Ligament Mechanobiology at the TU/e research group Orthopedic Biomechanics.