dr. S. (Sandra) Hofmann Boss - Expertise
P.O. Box 513
5600 MB EINDHOVEN
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Since 2013, Sandra Hofmann is an assistant professor in the Orthopaedic Biomechanics group of Prof. K. Ito at the Department of Biomedical Engineering, Eindhoven University of Technology.
She obtained her degree in Pharmaceutical Sciences from the University of Basel, Switzerland in 2002. After a scientific visit to Prof. D. Kaplan’s lab at Tufts University in Boston, she completed her PhD (with distinction) at the Department of Chemistry and Applied Sciences of the Swiss Federal Institute of Technology (ETH) in Zürich in 2007 working on silk fibroin as a biomaterial for drug delivery and tissue engineering. Subsequently, she moved to the group of Prof. R. Müller at the Institute for Biomechanics to advise a group of students and to focus her studies on imaging methods and bioreactor design. She currently is the Head of the Tissue Engineering and Regenerative Medicine Group, one of the three thematic divisions within the Laboratory for Bone Biomechanics. Since her move to Eindhoven, she still has a part-time appointment as lecturer at ETH Zürich.
She is involved in various EU and Swiss National Science Foundation founded research collaborations and was recently awarded and ERC starting grant (2013), a Marie Curie Career Integration grant (2013) as well as a Women in Science grant (2014). Sandra is also a core member of the Institute for Complex Molecular Systems (ICMS) at the TU/e and still has an appointment as a lecturer at ETH Zürich.
Current research topics are tissue engineering of skeletal tissues with a particular interest on mechano-biological questions, such as how mechanical loads are applied to and sensed by cells in a 3D environment and how the cells react to these in terms of matrix production. Within that context, her group investigates into bioreactor design, the application of mechanical loads, longitudinal monitoring approaches (especially micro-computed tomography) and the interaction between bone forming and bone resorbing cells.