Jan de Boer
Department / Institute
Group
RESEARCH PROFILE
Jan de Boer is full professor at the department of Biomedical Engineering, where he leads the research group BioInterface Science. He is an experienced University Professor and Chief Scientific Officer with a demonstrated history of working in academia and biotech. As a research professional he is skilled in Stem Cells, Biomaterial Engineering and Regenerative Medicine.
Jan is interested in the molecular complexity of cells and how molecular circuits are involved in cell and tissue function. With a background in mouse and Drosophila genetics, he entered the field of biomedical engineering in 2002 and has since focused on understanding and implementing molecular biology in the field of tissue engineering and regenerative medicine. His research is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology, to streamline the wealth of biological knowledge to real clinical applications.
Nature is stunningly beautiful, mysteriously complex and so effective that learning from it is pure joy.
ACADEMIC BACKGROUND
Jan de Boer obtained his MSc degree Biology at Utrecht University in 1994. He then started his PhD research in the lab of Prof. Jan Hoeijmakers on the genetics of ageing at the department of Cell Biology and Genetics, Erasmus University Rotterdam. Next, he moved to the MRC Laboratory of Molecular Biology (Cambridge, UK) where he worked as postdoctoral research fellow in Drosophila genetics. He returned to the Netherlands in 2002 to become a senior research scientist at the biotech company IsoTis, which was founded by Prof. Clemens van Blitterswijk with whom he collaborated until October 2018 when he moved to Eindhoven. In 2003, he became associate professor at the University of Twente and was awarded an NWO-VIDI grant in 2007. In 2012/2013 he spent a year as visiting scientist at the Broad Institute and Wyss Institute in Boston, MA, USA. In 2014, Jan de Boer was appointed full professor of Cell Biology-inspired Tissue Engineering at the Merln Institute of Maastricht University. Jan de Boer is co-founder and Chief Scientific Officer of the biotech company Materiomics, established in 2009 as a spin-off of his work at the University of Twente. Materiomics exploits the 'TopoChip' technology to design and identify the best surface for improved functionality and durability of medical and cell culture devices.
Recent Publications
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Ralph J.S. van Mechelen,Phani Sudarsanam,Christian J.F. Bertens,Mehmet O. Tas,Marion J.J. Gijbels,Leonard Pinchuk,Jan de Boer,Henny J.M. Beckers
The Influence of Design Modifications and Microstructured Surface Topographies on Bleb Survival after Glaucoma Tube Shunt Implantation
Advanced Biology (2023) -
Rio P. Juni,Jordy M.M. Kocken,Ricardo C. Abreu,Lara Ottaviani,Tim Davalan,Burcu Duygu,Ella M. Poels,Aliaksei Vasilevich,Jana C. Hegenbarth,Mahesh Appari
MicroRNA-216a is essential for cardiac angiogenesis
Molecular Therapy (2023) -
Aysegul Dede Eren,Steven Vermeulen,Tara C. Schmitz,Jasper Foolen,Jan de Boer
The loop of phenotype
Acta Biomaterialia (2023) -
Steven Vermeulen,Bart Van Puyvelde,Laura Bengtsson del Barrio,Ruben Almey,Bernard K. van der Veer,Dieter Deforce,Maarten Dhaenens,Jan de Boer
Micro-Topographies Induce Epigenetic Reprogramming and Quiescence in Human Mesenchymal Stem Cells
Advanced Science (2023) -
Jorge Alfredo Uquillas,Janne Spierings,Aysegul Dede Eren,Manon Bertrand,Hao Yuan,Huipin Yuan,Bart van Groningen,Rob Janssen,Keita Ito,Jan de Boer
An off-the-shelf decellularized and sterilized human bone-ACL-bone allograft for anterior cruciate ligament reconstruction
Journal of the Mechanical Behavior of Biomedical Materials (2022)
Ancillary Activities
No ancillary activities