Jelle Sleeboom is a PhD candidate in two different research groups: prof.dr. Carlijn Bouten's Soft Tissue Engineering & Mechanobiology (STEM) group, and prof.dr.ir. Jaap den Toonder's Microsystems group. His current research focuses on developing "breast-cancer-on-a-chip" technology to study the mechanisms that underlie cancer metastasis, in close collaboration with dr.Cecilia Sahlgren. His personal research interests are in developing and understanding microfabrication methods, microfluidics, organ-on-chip technology, mechanobiology, the Notch pathway, and cancer-on-chip technology.
Jelle Sleeboom, born in Utrecht in 1989, obtained his BSc in Mechanical Engineering at Eindhoven University of Technology in 2012. During his final bachelor project, under supervision of dr. Hans Wyss, he contributed to microfluidic single particle trapping and squeezing technology. His sparked interest in microfluidic technology drove him to join prof.dr.ir. Jaap den Toonder's Microsystems group as an MSc student in 2013. During his time in the group, he spent several months abroad at Harvard's Wyss Institute in Boston, USA, where he worked on a microfluidic model of the Blood Brain Barrier. After graduating (with honors) in the brain-on-a-chip project of dr. Regina Luttge, he started his joint PhD in the Soft Tissue Engineering & Mechanobiology (STEM) and Microsystems groups in 2016.
MDA-MB-231 breast cancer cells and their CSC population migrate towards low oxygen in a microfluidic gradient deviceInternational Journal of Molecular Sciences (2018)
Metastasis in contextDisease Models & Mechanisms (2018)
Compression and reswelling of microgel particles after an osmotic shockPhysical Review Letters (2017)
A novel breast-cancer model of early stage invasion(2017)
Compression and reswelling of microgel particles after an osmotic shockarXiv.org, e-Print Archive, Physics (2016)
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