Development of design & fabrication technologies that enable the local control of (bio) material composition and structure across multiple length scales is fundamental to understand complex regenerative processes in the human body; as well as to develop approaches for functional restoration of damaged&diseased tissues and organs. To address this challenge, Castilho team uses a material-by-design approach, combining advanced 3D printing technologies and computational design, to develop instructive materials for regenerative medicine, particularly of musculoskeletal tissues, like bone. Castilho’s research is interdisciplinary, bringing together engineers, materials scientists and cell biologists. An important focus area of the team is on exploring opportunities for translation of instructive materials in human clinics.
Miguel Castilho is an Assistant Professor of Biomaterials design and processing at TU/e. He holds a MSc degree in Mechanical Engineering and a PhD in Biomedical engineering (cum laude) from the University of Lisbon (IST, Portugal). During his PhD studies he was a visiting researcher at Department for Functional Materials in Medicine and Dentistry, University of Würzburg (Germany), in the field of Bioactive inorganic materials design and 3D printing. From 2015 - 2018 he was a post-doctoral research fellow in 3D Printing and Biofabrication at the University Medical Center Utrecht (UMC Utrecht, The Netherlands), to become an Assistant professor at UMC Utrecht and at the Regenerative Medicine Center (The Netherlands) from 2018 – 2021. In 2021 he started a tenured position as an Assistant Professor in the Department of Biomedical Engineering at TU/e, and holds an adjunct appointment in Biofabrication at UMC Utrecht.
Unveiling the potential of melt electrowriting in regenerative dental medicineActa Biomaterialia (2023)
Covalent Protein Immobilization on 3D-Printed Microfiber Meshes for Guided Cartilage RegenerationAdvanced Functional Materials (2023)
Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissuesBioactive Materials (2023)
Self-assembling peptide-laden electrospun scaffolds for guided mineralized tissue regenerationDental Materials (2022)
Injectable and adhesive hydrogels for dealing with woundsExpert Opinion on Biological Therapy (2022)
Current Educational Activities
- Adjunct Assistant professor, University Medical Center Utrecht, The Netherlands
- Member of Scientific Leadership Committee, International Society of Bone Morphometry